The only available text to focus primarily on Acute Respiratory Distress Syndrome (ARDS).
Thoroughly revised content and ten new chapters provide pulmonologists with the latest developments and applications of pharmacological and mechanical therapies needed to treat the debilitating and difficult condition of ARDS.
Highlights include:
- the definition, epidemiology, pathology, and pathogenesis of ARDS
- complications such as transfusion-related injury, and endothelium and vascular dysfunction
- the long-term outcomes of ARDS
- host defense and infection
- the latest developments in ARDS therapy: glucocorticoid therapy, surfactant therapy, mechanical ventilation, and mesenchymal stem cells
- predictive factors: gene expression profiling and biomarkers, and chemokines and cytokines
- advances in management strategies: fluid management, non-pulmonary and non-sepsis management, and glucose control
Definitions and Clinical Risk Factors
Marc Moss and B. Taylor Thompson
Epidemiology of Acute Lung Injury: A Public Health Perspective
Gordon D. Rubenfeld and Margaret J. Neff
Radiographic Findings of the Acute Respiratory Distress Syndrome
Philip C. Goodman and Desir?ee M. Qui?nones
Pulmonary Pathology of ARDS: Diffuse Alveolar Damage
Lester Kobzik and Lynette Sholl
Pathogenesis of Acute Lung Injury: Experimental Studies
Rebecca M. Baron and Mark A. Perrella
Pathogenesis of Acute Lung Injury: Clinical Studies
Benedict C. Creagh-Brown and Timothy W. Evans
Apoptosis in the Pathogenesis and Resolution of Acute Lung Injury
Gustavo Matute-Bello and Thomas R. Martin
Pathogenesis of Ventilator-Induced Lung Il³‡