Giving an overview of the challenges in the control of bioprocesses, this comprehensive book presents key results in various fields, including: dynamic modeling; dynamic properties of bioprocess models; software sensors designed for the on-line estimation of parameters and state variables; control and supervision of bioprocesses.
Chapter 1. What are the Challenges for the Control of Bioprocesses? 11
Denis DOCHAIN
1.1. Introduction . 11
1.2. Specific problems of bioprocess control 12
1.3. A schematic view of monitoring and control of a bioprocess 12
1.4. Modeling and identification of bioprocesses: some key ideas 13
1.5. Software sensors: tools for bioprocess monitoring 14
1.6. Bioprocess control: basic concepts and advanced control15
1.7. Bioprocess monitoring: the central issue 15
1.8. Conclusions 16
1.9. Bibliography 16
Chapter 2. Dynamic Models of Biochemical Processes: Properties of Models 17
Olivier BERNARD and Isabelle QUEINNEC
2.1. Introduction 17
2.2. Description of biochemical processes 18
2.2.1. Micro-organisms and their use 18
2.2.2. Types of bioreactors 19
2.2.3. Three operating modes 19
2.3. Mass balance modeling 21
2.3.1. Introduction 21
2.3.2. Reaction scheme 21
2.3.3. Choice of reactions and variables 23
2.3.4. Example 1 23
2.4. Mass balance models 24
2.4.1. Introduction 24
2.4.2. Example 2 24
2.4.3. Example 3 25
2.4.4. Matrix representation 25
2.4.4.1. Exampll#&