This volume is a valuable and timely resource for a broad audience with interests in basic and translational cancer biology, cancer drug development, as well as in the practice of personalized oncology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, Cancer Gene Networks aims to ensure successful results in the further study of this evolving and vital field. Ultimately these efforts will guide development of transformative strategies for cancer diagnosis and treatment.
1. Introduction- Cancer Gene Networks
Robert Clarke
2. Emerging Methods in Chemoproteomics with Relevance to Drug Discovery
Chuong Nguyen, Graham M. West, and Kieran F. Geoghegan
3. ANXA7-GTPase as Tumor Suppressor: Mechanisms and Therapeutic Opportunities
Ximena Leighton, Ofer Eidelman, Catherine Jozwik, Harvey B. Pollard, and Meera Srivastava
4. Experimental and Study Design Considerations for Uncovering Oncometabolites
Majda Haznadar and Ewy Math?
5. Targeting Deubiquitinating Enzymes and Autophagy in Cancer
Ashley Mooneyham and Martina Bazzaro
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