This book is a comprehensive, multi-authored work on the structure and function of the mammalian testis. The approach emphasizes gene expression, translation and production of specific gene products and the cellular and molecular regulation of these fundamental processes. Rather than provide a global survey of all aspects of male reproduction, this book stresses specific mechanisms that underscore the structure and function of the testis. It explains old and new concepts from a cellular and molecular perspective. This novel approach allows the authors to forge links between cell and molecular biology and well-established aspects of spermatogenesis and steroidogenesis. The result is a well-focused, comprehensive, and synthetic analysis of testicular biology.
1. Cell Biology of Testicular Development in the Fetus and Neonate,J.M. Orth 2. Molecular Genetics of the Human and Mouse Y-Chromosome,P.N. Goodfellow, et al. 3. Development of the Germ Cell,J.R. McCarrey 4. Genetic Control of Spermatogenesis and Steroidogenesis,C.E. Chubb 5. Mullerian Inhibiting Substance,P.K. Donahoe 6. Design and Function of the Microcirculation,C. Desjardins 7. Leydig Cell:Structure/Function,L.L. Ewing 8. Regulation of Spermatogenesis in the Adult Mammal: Gonadotropins and Androgens,B.R. Zirkin 9. The Cell Biology of the Sertoli Cell,C.W. Bardin, G. L. Gunsalus and C.Y. Cheng 10. Inhibin and Inhibin-related Proteins,D.M. Robertson, G.P. Risbridger, and D.M. de Kretser 11. The Seminiferous Tubular Microenvironment,B.T. Hinton and T.T. Turner 12. Spermatogonial Stem Cells,M.L. Meistrich and M.E.A.B. van Beek 13. The Process of Meiosis,H. Stern 14. Cell Biology of Mammalian Spermiogenesis,Y. Clermont, R. Oko, and L. Hermo 15. Cellular Interactions in the Seminiferous Epithelium,W.W. Wright 16. Gene Expression DlCI