Natural products play crucial roles in modern drug development, and constitute a prolific source of novel lead compounds or pharmacophores for ongoing drug discovery programs. Chemistry and Pharmacology of Naturally Occurring Bioactive Compoundspresents cutting-edge research in the chemistry of bioactive natural products and demonstrates how natural product research continues to make significant contributions in the discovery and development of new medicinal entities.
In 21 chapters, this book highlights chemistry and pharmaceutical potential of natural products in modern drug discovery processes, and covers the synthesis and semi-synthesis of potentially bioactive natural products. Written for phytochemists, synthetic chemists, combinatorial chemists, as well as other practitioners and students in related fields, the book features chemical advances in naturally occurring organic compounds and describes their chemical transformations and structureactivity relationships.
Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds
Goutam Brahmachari
Impact of Solid-Supported CyclizationElimination Strategies toward the Development of Natural Product Inspired Molecules in Drug Discovery Research
Dhananjay Kumar, Bhuwan B. Mishra, Divya Kushwaha, and Vinod K. Tiwari
Synthesis and Biological Studies of Novel ?-Lactams Bimal K. Banik
Applications of Isatin Chemistry in Organic Synthesis and Medicinal Chemistry
Girija S. Singh and Zelalem Y. Desta
Role of Organic Carbamates in Anticancer Drug Design
Devdutt Chaturvedi
Rational Design of New Molecules of Biological Significance from Phenolic Constituents of Some Tropical Plants as Renewable Materials
Vladimir V. Kouznetsov, Diego R. Merchanl³g