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Computational Protein Design [Paperback]

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  • Category: Books (Science)
  • ISBN-10:  1493982567
  • ISBN-10:  1493982567
  • ISBN-13:  9781493982561
  • ISBN-13:  9781493982561
  • Publisher:  Humana
  • Publisher:  Humana
  • Binding:  Paperback
  • Binding:  Paperback
  • Pub Date:  01-Apr-2018
  • Pub Date:  01-Apr-2018
  • SKU:  1493982567-11-SPRI
  • SKU:  1493982567-11-SPRI
  • Item ID: 101356890
  • List Price: $129.99
  • Seller: ShopSpell
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The aim this volume is to present the methods, challenges, software, and applications of this widespread and yet still evolving and maturing field. Computational Protein Design, the first book with this title, guides readers through computational protein design approaches, software and tailored solutions to specific case-study targets. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Computational Protein Design aims to ensure successful results in the further study of this vital field.

Part I: Computational Protein Design
1.The Framework of Computational Protein Design
Ilan Samish

2.Achievements and Challenges in Computational Protein Design
Ilan Samish

3.Production of Computationally Designed Small Soluble- and Membrane-Proteins: Cloning, Expression and Purification
Barsha Tripathy and Rudresh Acharya

4.Deterministic Search methods for Computational Protein Design
Seydou Traor?, David Allouche, Isabelle Andr? Thomas Schiex, and Sophie Barbe

5.Geometric Potentials for Computational Protein Sequence Design
Jie Li and Patrice Koehl 

6.Modeling Binding Affinity of Pathological Mutations for Computational Protein Design
Miguel Romero-Durana, Chiara Pallara, Fabian Glaser, and Juan Fern?ndez-Recio

7.MultistatlÓ*