Enzymes of Epigenetics [Hardcover]

Enzymes of Epigenetics, one of two new volumes in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field.

This volume covers research methods that are employed to study epigenetic regulation and includes structural, biochemical, molecular, biological, cellular, computational, and systems approaches.

Topics include chromatin structure and histones, posttranslational histone modification enzymes and complexes, histone modification binders, DNA modifications and nucleic acid regulators, epigenetic technologies and small molecule epigenetic regulators, and biological connections

• Continues the legacy of this premier serial with quality chapters authored by leaders in the field
• Contains two new volumes covering research methods in enzymes of epigenetics
• Covers topics such as chromatin structure and histones, posttranslational histone modification enzymes and complexes, histone modification binders, DNA modifications and nucleic acid regulators, epigenetic technologies and small molecule epigenetic regulators and biological connections

Chromatin Structure and Histones 1.?In Vitro Chromatin Assembly - Strategies and Quality Control Uma Muthurajan, Francesca Mattiroli, Serge Bergeron, Keda Zhou, Yajie Gu, Srinivas Chakravarthy, Pamela Dyer, Thomas Irving and Karolin Luger 2.?Preparation, Crystallization and Structure Determination of Chromatin Enzyme/Nucleosome Complexes Robert K. McGinty, Ravindra D. Makde and Song Tan 3.?Preparation of Recombinant Centromeric Nucleosomes and Formation of Complexes with Non-Histone Centromere Proteins Nikolina Sekulic and Ben E. Black 4.?Functional? Characterization? of? Histone Chaperones using SNAP-Tag-Based Imaging to Assess De Novo Histone Deposition CamillÃ&