Enzymes of Epigenetics Part B [Hardcover]

Enzymes of Epigenetics: Part B, one of two new volumes in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field.

This volume covers research methods that are employed in the study of epigenetic regulation, including structural, biochemical, molecular, biological, cellular, computational, and systems approaches.

Topics include chromatin structure and histones, posttranslational histone modification enzymes and complexes, histone modification binders, DNA modifications and nucleic acid regulators, epigenetic technologies, and small molecule epigenetic regulators and biological connections.

• Continues the legacy of this premier serial with quality chapters authored by leaders in the field
• Contains two new volumes that cover research methods in enzymes of epigenetics
• Covers such topics as chromatin structure and histones, posttranslational histone modification enzymes and complexes, histone modification binders, DNA modifications and nucleic acid regulators, epigenetic technologies and small molecule epigenetic regulators, and biological connections

Epigenetic Technologies 1.?Identification and Quantification of Histone PTMs using High-Resolution Mass Spectrometry Kelly R. Karch, Simone Sidoli and Benjamin A. Garcia 2.?Substrate Specificity Profiling of Histone-Modifying Enzymes by Peptide Microarray Evan M. Cornett, Bradley M. Dickson, Robert M. Vaughan, Swathi Krishnan, Raymond C. Trievel, Brian D. Strahl, and Scott B. Rothbart 3.?ArrayNinja: An Open Source Platform for Unified Planning and Analysis of Microarray Experiments Bradley M. Dickson, Evan M. Cornett, Zachary Ramjan and Scott B. Rothbart 4.?Chemical Biology Approaches for Characterization of Epigenetic Regulators Dalia Barsyte-lÃ&