The Genetics of Male Infertility [Hardcover]

In this book, twenty-one researchers and clinicians review the study of the genetics of male infertility, the tools available in the laboratory and clinic, the current state of knowledge, and the future of research and translation into clinical diagnostics and treatments.

New tools discussed are discussed. This book therefore serves as a guide to evidence-based clinical applications, and a preview of future possibilities.

Infertility is a common and severe health problem affecting roughly 7% of the male population. It is likely that the majority of those patients have genetic abnormalities that are the cause of their infertility. In The Genetics of Male Infertility, twenty-one researchers and clinicians review the study of the genetics of male infertility, the tools available in the laboratory and clinic, the current state of knowledge, and the future of research and translation into clinical diagnostics and treatments.

This volume gives special attention to the significant technological advances in the treatment of male infertility, including intracytoplasmic injection (ICSI) in conjunction with in vitro fertilization (IVF). In addition, new tools discussed include in vitro methodologies, in silico technologies, and new model organisms.

Providing a review of our current understanding of genetic causes of male infertility, The Genetics of Male Infertility serves as a guide to evidence-based clinical applications, and a preview of future possibilities.

Genetics of Male Infertility Table of Contents Preface Douglas T. Carrell, Ph.D. Methods and Tools for the Study of the Genetics of Male Infertility 1. The Genetics of Male Infertility in the Era of Genomics: Tools for Progress Douglas T. Carrell, Ph.D. Abstract 1. Genetics and Andrology: Collaboration Between Two Fields 2. The Contribution of the Human Genome Project 3. The Identification and Evaluation of Candidate Male Infertill£‡