High Throughput Screening The Discovery of Bioactive Substances [Hardcover]

Furnishing the latest interdisciplinary information on the most important and frequently the only investigational system available for discovery programs that address the effects of small molecules on newly discovered enzyme and receptor targets emanating from molecular biology, this timely resource facilitates the transition from classical to high throughput screening (HTS) systems and provides a solid foundation for the implementation and development of HTS in bio-based industries and associated academic environments.Natural Products as a Discovery Resource, edited by John P. Devlin


Chemical Diversity and Genetic Equity: Synthetic and Naturally Derived Compounds, John P. Devlin
Microcollection of Plants for Biochemical Profiling, John P. Devlin
Enzymes and Microbes as a Source of Chemical Diversity, Saul L. Neidleman
The Marine Environment as a Discovery Resource, Gregg R. Dietzman


Compound Sourcing: Chemically Generated Screening Libraries, edited by Michael R. Pavia


Introduction, Michael R. Pavia
Rapidly Expanding Molecular Diversity: Libraries from Libraries, John S. Kiely, Barbara D?rner, John M. Ostresh, Colette Dooley, and Richard A. Houghten
Synthesis of Encoded Small Molecule Combinatorial Libraries via ECLiPS, Jack J. Baldwin and Ian Henderson
Parallel Organic Synthesis Using Parke-Davis' Diversomer? Method, Sheila Hobbs DeWitt and Anthony W. Czarnik
Rapid Discovery and Optimization of Biologically Active Small Molecules Using Automated Synthesis Methods, Adnan M. M. Mjalli and Barry E. Toyonaga
CMT: A Solution Phase Combinatorial Chemistry Approach: Synthesis and Yield Prediction Phenazines, Ferenc Darvas and L?szl? Kov?cs
Design of a Diverse Screening Library, David E. Patterson, Allan M. Ferguson, Richard D. Cramer, Cheryl D. Garr, Ted L. Underiner, and John R. Peterson
Automating Combinatorial Chemistry: Challenges and Pitfalls, Jilll3Ê