Human Gene Evolution [Hardcover]

Presents the principles of human gene evolution in a concise and easy to understand fashion. Uses examples of how evolutionary processes have molded present day genes, drawn from the evolution of humans and other primates, as well as from more primitive organisms. With increasing attention in this expanding area, this review forms a timely publication of our current knowledge of this important field.

• Structure and function in the human genome
• The evolution of gene structure
• Mutational mechanisms in evolution

Preface.
Abbreviations.
Introduction and Overview:
Structure and Function in the Human Genome.
Evolution of the Human Genome.
Evolution of Gene Structure:
Introns, Exons and Evolution.
Genes and Gene Families.
Promoters and Transcription Factors.
Pseudogenes and their Formation.
Mutational Mechanisms in Evolution:
Single Base-pair Substitutions.
Contractions and Expansions in Gene Size and Number.
Gross Gene Rearrangements.
Molecular Reconstruction of Ancient Genes/Proteins.
Indices of Human Gene Symbols used in the text.
Index.The Human Genome Project is soon expected to yield the entire sequence of the human genome, providing an unparalleled opportunity to understand its structure, function and evolution. Human Gene Evolution bring together the highly dispersed literature on human gene structure, function, organization and expression, integrates this with our emerging knowledge of chromosome and genome structure, and discusses the nature of the mutational mechanisms that underlie evolutionary change.
A companion volume to the best-selling Human Gene Mutation by the same author, a central theme to this book is that mulã€