This book, originally published in 2004, is concerned with the links between human evolution and infectious disease.It has long been recognized that an important factor in human evolution has been the struggle against infectious disease. From the historical beginnings of Haldane's original hypothesis to current research, this book strives to evaluate infectious diseases from an evolutionary perspective. It provides a survey of the latest information related to major infections, such as malaria, influenza and leishmaniasis. Written by leading authorities in the field, this unique reference will appeal to those working in microbiology, parasitology, immunology and infectious disease medicine, as well as genetics, evolutionary biology and epidemiology.It has long been recognized that an important factor in human evolution has been the struggle against infectious disease. From the historical beginnings of Haldane's original hypothesis to current research, this book strives to evaluate infectious diseases from an evolutionary perspective. It provides a survey of the latest information related to major infections, such as malaria, influenza and leishmaniasis. Written by leading authorities in the field, this unique reference will appeal to those working in microbiology, parasitology, immunology and infectious disease medicine, as well as genetics, evolutionary biology and epidemiology.From the historical beginnings of Haldane's original hypothesis to current research, this book evaluates infectious diseases from an evolutionary perspective. It surveys the latest information related to major infections, such as malaria, influenza and leishmaniasis.Part I. J. B. S. Haldane: 1. Haldane's ideas in biology with special reference to disease and evolution James F. Crow; 2. JBS Haldane and the malaria hypothesis D. J. Weatherall; Part II. malarial parasites: 3. Evolutionary genetics of Plasmodium Falciparum, the agent of malignant malaria Stephen M. Rich and Francisco J. Ayala;l#/