An integrated study of esophageal cancer has been presented in this detailed book. Esophageal Cancer discusses latest developments and investigations in the esophageal tumorigenesis from different perspectives. This book provides various techniques involved in esophageal tumorigenesis, cellular, molecular, genetic, epigenetics and proteomics and their importance as the new biomarkers and utilization in esophageal cancer diagnosis and therapy. This book encompasses comprehensive effect of nutritional factors in addition to ethanol metabolic pathway in the inhibition of retinoic acid metabolism and supply. Diagnosis, classification and treatment of esophageal cancer, application of both surgical and non-surgical approaches as well as follow-ups of the disease have been described in detail. Moreover, readers have been provided with exclusive aspects of esophageal cancer like multiple early stage malignant melanoma and pulmonary edema induced by esophagectomy; the two features which usually receive less attention in texts on esophageal cancer.