Behavioral Neurobiology of Schizophrenia and Its Treatment [Paperback]

This book describes the state-of-the-art of treatment of schizophrenia and reflects its development in 22 chapters written by leading authorities in the field

Written by leading authorities in the field, this book describes the state-of-the-art of treatment of schizophrenia and reflects its development. It provides new tools to access and target real-life function and functional outcome in the schizophrenia.

Assessing Function and Functional Outcome in Schizophrenia.- Antipsychotics and Metabolics in the Post-CATIE Era.- Pharmacological Strategies for Enhancing Cognition in Schizophrenia.- Treatment Implications of the Schizophrenia Prodrome.- Antipsychotic Drug Development.- Antipsychotic Dosing and Drug Delivery.- Functional Brain Imaging in Schizophrenia: Selected Results and Methods.- Neurochemical Imaging in Schizophrenia.- A Selective Review of Volumetric and Morphometric Imaging in Schizophrenia.- Neurophysiological Measures of Sensory Registration, Stimulus Discrimination, and Selection in Schizophrenia Patients.- Eye Tracking Dysfunction in Schizophrenia: Characterization and Pathophysiology.- Prepulse Inhibition of the Startle Reflex: A Window on the Brain in Schizophrenia.- Neurocognition in Schizophrenia.- Animal Models of Schizophrenia.- Models of Neurodevelopmental Abnormalities in Schizophrenia.- Prefrontal Cortical Circuits in Schizophrenia.- Thalamic Pathology in Schizophrenia.- Hippocampal Pathology in Schizophrenia.- Integrative Circuit Models and Their Implications for the Pathophysiologies and Treatments of the Schizophrenias.- Experimental Approaches for Identifying Schizophrenia Risk Genes.- Epigenetics of Schizophrenia.- Molecules, Signaling, and Schizophrenia.Schizophrenia research is in a dynamic state; this text gives a foothold for where we stand today, and a map for where our field may move tomorrow. Chapters on treatment describe major changes in clinical and neural targets, and new technologies for drug delivery, even l#K