Immunology of HIV Infection [Hardcover]

Leading experts provide the only comprehensive book examining all aspects of immune response and immune-based treatments for HIV infection. Contributions, divided into three sections, discuss basic mechanisms, immunopathogenesis of HIV infection, and immune-based therapies. Researchers thoroughly review vaccine-including prospects of T cell vaccine-and gene therapy for HIV infection. Additional topics include organization of HIV genes, the role of co-receptors in signaling of lymphocytes, and biological response modifiers. This reference is designed for basic and clinical researchers, internists, pediatricians, infectious disease specialists, neuropathologists, oncologists, and rheumatologists.Leading experts provide the only comprehensive book examining all aspects of immune response and immune-based treatments for HIV infection. Contributions, divided into three sections, discuss basic mechanisms, immunopathogenesis of HIV infection, and immune-based therapies. Researchers thoroughly review vaccine-including prospects of T cell vaccine-and gene therapy for HIV infection. Additional topics include organization of HIV genes, the role of co-receptors in signaling of lymphocytes, and biological response modifiers. This reference is designed for basic and clinical researchers, internists, pediatricians, infectious disease specialists, neuropathologists, oncologists, and rheumatologists.Basic Mechanisms: Genetic Organization of HIV; L. Ratner. T Cell Epitopes in the HIV1 Envelope Glycoprotein; R.F. Siliciano. B Cell in the HIV Glycoproteins; E. Bj?rling, E. Norrby. Lymphocyte Adhesion Coreceptors and Their Roles in HIV1 Replication; J.A. Ledbetter. Immunopathogenesis: HIV and Lymph Node and Thymus; D.D. Patel, et al. Effects of HIV1 and HIV1 Glycoproteins on Signalling Pathways in Human T Lymphocytes; S. Gupta. Lymphocyte Apoptosis in HIV Infection; N. Oyaizu, S. Pahwa. Biological Activities of HIVspecific Peptides; S. Schwartz, et al. Phenol3¦