Maturation Phenomenon in Cerebral Ischemia II: Neuronal Recovery and Plasticity [Paperback]

Many nerve cells of the brain which are not killed outright may suffer delayed death or recovery after ischemic insult. This fact has led to the concept of maturation phenomenon of neuronal injuries. Since the 1st International Symposium on Maturation Phenomenon in 1990, new developments, particularly in molecular biology, have been rapidly bringing new information about molecular nature and mechanisms of cell death. This book contains the presentations of the 2nd International Symposium held in Tokyo in April 1996. The latest developments in maturation phenomenon and the present status of investigation are described and further stimulation of research in this field is provided.Many nerve cells of the brain which are not killed outright may suffer delayed death or recovery after ischemic insult. This fact has led to the concept of maturation phenomenon of neuronal injuries. Since the 1st International Symposium on Maturation Phenomenon in 1990, new developments, particularly in molecular biology, have been rapidly bringing new information about molecular nature and mechanisms of cell death. This book contains the presentations of the 2nd International Symposium held in Tokyo in April 1996. The latest developments in maturation phenomenon and the present status of investigation are described and further stimulation of research in this field is provided.I Role of Genetic Expression  Changes in Maturation Phenomenon.- Molecular Approaches to Neuronal Functions and Neuronal Cell Death.- Evolution of Gene Expression in Hippocampus Following Focal and Global Ischemia.- Synaptic Messengers, Inflammatory Mediators, and Neuronal Plasticity in Cerebral Ischemia.- Ischemic Neuronal Injury and Gene Expression of Facilitative and Inhibitory Growth Factors.- Is Apoptosis Involved in Glutamate Neurotoxicity?.- II Factors and Mechanisms Enhancing Susceptibility or Tolerance.- Glutamate Enhances Brain Damage from Ischemia and Trauma.- Glutamate-Mediated Mechanisms in Delayed NelS!