This is a comprehensive book which aims to present state-of-the-art information regarding microangiopathy. Microangiopathies are pathological processes which cause degenerative diseases of small vessels. The circulatory constraints caused by microangiopathies may be accountable for the collapse of single or multiple organs. These pathological processes are one of the most common disorders characterized by high morbidity and mortality in the affected patients. Various research outcomes have reflected intricate processes both at cellular and molecular level. However, the diversity among varied pathogenetic mechanisms leading to microangiopathic disorders is yet to be explained to equip practitioners with effective prevention and treatment strategies. This book provides descriptive examples of relevant mechanisms responsible for different forms of microangiopathies and how this body of evidences can be evaluated to define new strategies of therapeutic intervention.