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A pioneering group of authors describes in this book, for the first time, the state of the art of spinal cord stimulation for chronic critical limb ischemia. This method, a progeny of pacemaking in cardiac rhythm disorders, is a promising, innovative procedure; it presents a modern challenge in treatment of endstage peripheral vascular disease or neuropathic pains. Spinal cord stimulation may have a tremendous future if it further develops to become a standard treatment in special indications.A pioneering group of authors describes in this book, for the first time, the state of the art of spinal cord stimulation for chronic critical limb ischemia. This method, a progeny of pacemaking in cardiac rhythm disorders, is a promising, innovative procedure; it presents a modern challenge in treatment of endstage peripheral vascular disease or neuropathic pains. Spinal cord stimulation may have a tremendous future if it further develops to become a standard treatment in special indications.Anatomy, physiology and pharmacology of pain.- Basic neurophysiological mechanisms of pain and pain control.- The endogenous neuromodulatory system.- Some aspects on pathophysiology of pain in clinical angiology.- Spinal cord stimulation for chronic pain.- Spinal cord stimulation in patients: Basic anatomical and neurophysiological mechanisms.- Neuropathic pain and stimulation of the nervous system.- Spinal cord stimulator: Design and function.- Epidural spinal cord stimulation (ESCS): Implantation technique.- Critical limb ischemia.- Definition, epidemiology, and pathophysiology of critical limb ischemia.- Pharmacotherapy of critical limb ischemia.- Limb salvage, vascular procedures versus primary amputation.- Assessment of the microcirculation.- Evaluation of the skin microcirculation by photoplethysmography, laser Doppler velocimetry, and transcutaneous measurements of pO2.- Laser doppler fluxmetry in peripheral vascular disease.- Clinical evaluations.- Transcutaneous oxygen tension in lÓ+
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