Sepsis and Organ Dysfunction: Bad and Good News on Prevention and Management [Paperback]

Sepsis evolution and organ dysfunction are still an enigmatic topic. Severe infection causes an important aggression of the whole body, and the so-called inflammation mediators play an important role in this evolution. It is however certain that the immune system is a key factor in sepsis progression. The volume focuses on some primary aspects such as the research of the rationale of the immune system activation during sepsis, on the molecular strategies available for ARDS treatment and on techniques of emofiltration and absorption of endotoxins through apheresis in the septic patient.Sepsis evolution and organ dysfunction are still an enigmatic topic. Severe infection causes an important aggression of the whole body, and the so-called inflammation mediators play an important role in this evolution. It is however certain that the immune system is a key factor in sepsis progression. The volume focuses on some primary aspects such as the research of the rationale of the immune system activation during sepsis, on the molecular strategies available for ARDS treatment and on techniques of emofiltration and absorption of endotoxins through apheresis in the septic patient.Epidemiology of Infections in ICUs: Where Are We?.- Prothrombin Fragment 1+2 Levels Are Associated with Pulmonary and Renal Responses to Cardiopulmonary Bypass.- Oxidative Stress and Apoptosis in Sepsis and the Adult Respiratory Distress Syndrome.- Neutrophil Defensins in Lung Inflammation.- Nitric Oxide: Lessons Learned and Areas of Success.- Protecting Renal Blood Flow in the Intensive Care Unit.- Bad and Good News in Pathophysiology, Prevention, and Management of Sepsis.- Light and Shadow: Perspectives on Host-Microbial Interactions in the Pathogenesis of Intensive Care Unit-Acquired Infection.- Identification and Characterization of Protein Tyrosine Phosphatases Expressed in Human Neutrophils.- Treatment of Sepsis and Endotoxemia by Extracorporeal Endotoxin Adsorption with Immobilised Human Serum Albul+