Macromolecular Crystallography, Part A [Hardcover]

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 270 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences.

• Crystal Growth
• Phase Determination
• Instrumentation and Data Collection
• Model Building
• Refinement

Introduction: B.W. Matthews, Recent Transformations in Structural Biology. Crystals: P.C. Weber, Overview of Protein Crystallization Methods. M. Rigs-Kautt and A. Ducruix, Inferences Drawn from Physicochemical Studies of Crystallogenesis and Precrystalline State. L. Song and J.E. Gouaux, Membrane Protein Crystallization: Application of Sparse Matrix to alpha-Hemolysin Heptamer. C.W. Carter, Jr., Response Surface Methods for Optimizing and Improving Reproducibility of Crystal Growth. A. George, Y. Chiang, B. Guo, A. Arabshahi, Z. Cai, and W.W. Wilson, Second Virial Coefficient as Predictor in Protein Crystal Growth. J.R. Luft and G.T. DeTitta, Kinetic Aspects of Macromolecular Crystallization. R. Sousa, Using Cosolvents to Stabilize Protein Conformation for Crystallization. C.E. Kundrot, Preparation and Crystallization of RNA: A Sparse Matrix Approach. A.R. Ferre-Damare and S.K. Burley, Dynamic Light Scattering in Evaluating Crystallizability of Macromolecules. A.M. Edwards, S.A. Darst, S.A. Hemming, ló›