Medical Epigenetics [Hardcover]

Medical Epigenetics provides a comprehensive analysis of the importance of epigenetics to health management. The purpose of this book is to fill a current need for a comprehensive volume on the medical aspects of epigenetics with a focus on human systems, epigenetic diseases that affect these systems and modes of treating epigenetic-based disorders and diseases. The intent of this book is to provide a stand-alone comprehensive volume that will cover all human systems relevant to epigenetic maladies and all major aspects of medical epigenetics. The overall goal is to provide the leading book on medical epigenetics that will be useful not only to physicians, nurses, medical students and many others directly involved with health care, but also investigators in life sciences, biotech companies, graduate students and many others who are interested in more applied aspects of epigenetics. Research in the area of translational epigenetics is a cornerstone of this volume.

• Critical reviews dedicated to the burgeoning role of epigenetics in medical practice
• Coverage of emerging topics including twin epigenetics as well as epigenetics of gastrointestinal disease, muscle disorders, endocrine disorders, ocular medicine, pediatric diseases, sports medicine, noncoding RNA therapeutics, pain management and regenerative medicine
• Encompasses a disease-oriented perspective of medical epigenetics as well as diagnostic and prognostic epigenetic approaches to applied medicine

Section I:? Overview

1.? An Overview of Medical Epigenetics ?Trygve O. Tollefsbol

Section II:? Basic Principles of Epigenetics

2.? DNA Methylation:? Basic Principles ?Cynthia A. Moylan and Susan K. Murphy

3.? Histone-deacetylases as a therapeutic target in neurodegenerative diseases ?Farahnaz Sananbenesi and Andre lÃ&