Medical Radiation Dosimetry: Theory of Charged Particle Collision Energy Loss [Paperback]

Accurate radiation dosimetry is a requirement of radiation oncology, diagnostic radiology and nuclear medicine.? It is necessary so as to satisfy the needs of patient safety, therapeutic and diagnostic optimisation, and retrospective epidemiological studies of the biological effects resulting from low absorbed doses of ionising radiation.? The radiation absorbed dose received by the patient is the ultimate consequence of the transfer of kinetic energy through collisions between energetic charged particles and atoms of the tissue being traversed.? Thus, the ability of the medical physicist to both measure and calculate accurately patient dosimetry demands a deep understanding of the physics of charged particle interactions with matter.? Interestingly, the physics of charged particle energy loss has an almost exclusively theoretical basis, thus necessitating an advanced theoretical understanding of the subject in order to apply it appropriately to the clinical regime.

 Each year, about one-third of the world's population is exposed to ionising radiation as a consequence of diagnostic or therapeutic medical practice. The optimisation of the resulting radiation absorbed dose received by the patient and the clinical outcome sought, whether diagnostic or therapeutic, demands accuracy in the evaluation of the radiation absorbed doses resulting from such exposures. This requirement arrises primarily from two broadly-encompassing factors:

• The requirement in radiation oncology for a 5% or less uncertainty in the calculation and measurement of absorbed dose so as to optimise the therapeutic ratio of the probabilities of tumour control and normal tissue complications; and
• The establishment and further refinement of dose reference levels used in diagnostic radiology and nuclear medicine to minimise the amount of absorbed dose for a required degree of diagnostic benefit.

Thelă5