Metal Catalyzed Cascade Reactions [Paperback]

This book highlights cyclization via carbopalladation and acylpalladation and Heck-pericyclic sequences. They discuss p-allyl palladium-based cascade reactions, Michael-type additions as an entry to transition-metal-promoted cyclizative transformations, and sequential or consecutive palladium-catalyzed processes, and show Pauson-Khand cascades, metal-catalyzed cyclizations of acyclic precursors, as well as cascade and sequential ruthenium-catalyzed transformations. This is a comprehensive overview of an exciting and highly dynamic, and innovative methodological concept.

With contributions by numerous expertsEi-Ichi Negishi, Guangwei Wang, and Gangguo Zhu: Palladium-Catalyzed Cyclization via Carbopalladation and Acylpalladation.- Paultheo von Zezschwitz, and Armin De Meijere: Domino Heck-Pericyclic Reactions.- Nitin T. Patil, and Yoshinori Yamamoto: Palladium Catalyzed Cascade Reactions Involving p-Allyl Palladium Chemistry.- Genevi?ve Balme, Didier Bouyssi, and Nuno Monteiro: The Virtue of Michael-Type Addition Processes in the Design of Transition Metal-Promoted Cyclizative Cascade Reactions.- Thomas J. J. M?ller: Sequentially Palladium Catalyzed Processes.- Javier P?rez-Castells: Cascade Reactions Involving Pauson-Khand and Related Processes.- Corinne Aubert, Louis Fensterbank, Vincent Gandon, and Max Malacria: Complex Polycyclic Molecules from Acyclic Precursors via Transition Metal-Catalyzed Cascade Reactions.- Christian Bruneau, Sylvie D?rien, and Pierre H. Dixneuf: Cascade and Sequential Catalytic Transformations initiated by Ruthenium Catalysts.

From the reviews:

This volume, the latest in the Topics in Organometallic Chemistry series, features reports from eight research groups active in cascade catalysis. It does not focus on particular reactions or periodic groups but rather offers a broad overview of methods to generate multiple bonds in a given organic molecule with stereo- and regiocontrol.lă&