Methods in Membrane Lipids [Paperback]

This book presents a compendium of methodologies for the study of membrane lipids, varying from traditional lab bench experimentation to computer simulation and theoretical models. The volume provides a comprehensive set of techniques for studying membrane lipids with a strong biophysical emphasis. It compares the various available techniques including the pros and cons as seen by the experts.

Methods in Membrane Lipids presents a compendium of methodologies for the study of membrane lipids, varying from traditional lab bench experimentation to computer simulation and theoretical models. This volume provides a comprehensive set of techniques for studying membrane lipids, and their interactions with other membrane lipids, with membrane proteins, and with exogenous agents such as anesthetics. The progression of chapters increases in complexity, initially presenting introductory concepts and methods for the study of simple structures and interactions, then moving to the study of more complex structures and interactions, including: behaviors of lipids in water systems and phases; membrane lipid movements and diffusion; properties of lipids in mono and bilayers; complex lipid domains; and membrane-lipid interaction with proteins and drugs. Each chapter is written by an internationally recognized expert in the field.

Methods in Membrane Lipids: Table of ContentsIntroductory Chapters:1 A glance at the structural and functional diversity of membrane lipidsAlejandro M. Dopico and Gabor J. Tigyi2 Membrane lipid polymorphism: relationship to bilayer properties andprotein functionRichard EpandLipid distribution, membrane lipid structure, and lipid-lipidinteractions:3 Acrylodan-labeled intestinal fatty acid binding protein to measureconcentrations of unbound fatty acidsJeffrey R. Simard, Frits Kamp, and James A. Hamilton4 Measuring molecular order and orientation using Coherent-anti StokesRaman scatteringmicroscopyHilde A. Rinia, George W.H. Wlsè