Morphogenesis The Cellular and Molecular Processes of Developmental Anatomy [Hardcover]

This book, first published in 1990, provides an overview of the events and mechanisms of morphogenesis.This textbook provides a contemporary overview of the events and mechanisms of morphogenesis, reviewing the major molecular and cellular mechanisms underlying morphogenetic change and describing how these processes are integrated during normal development.This textbook provides a contemporary overview of the events and mechanisms of morphogenesis, reviewing the major molecular and cellular mechanisms underlying morphogenetic change and describing how these processes are integrated during normal development.This timely account provides a comprehensive contemporary analysis of morphogenetic processes in vertebrate and invertebrate embryos. Morphogenesis, the generation of tissue organization in embryos, is an increasingly important subject. This is partly because the techniques for investigating many morphogenetic mechanisms have only recently become available and partly because studying the genomic basis of embryogenesis requires an understanding of the developmental phenotype. Following an introduction covering case studies and historical and technical approaches, the book reviews the mechanistic roles of extracellular matrices, cell membranes and the cytoskeleton in morphogenesis. A detailed discussion of how mesenchymal and epithelial cells cooperate to build a wide range of tissues is also included. The book concludes with a dynamical analysis of the subject. With its extensive literature review (more than 500 titles), this book will interest developmental biologists and will also serve as an advanced textbook for postgraduate and final year students.Preface; Acknowledgements; 1. Introduction; 2. Background; 3. Case studies; 4. The molecular basis of morphogenesis; 5. The morphogenetic properties of mesenchyme; 6. The epithelial repertoire; 7. A dynamic framework for morphogenesis; 8. Pulling together some threads; Appendices; References; Index. ...well wló›