A comparative discussion of A? and C fibres in different tissues.- The roles of spinal receptors in nociceptive responses.- Cutaneous hyperalgesia.- Capsaicin and pain mechanisms.- Nitric oxide and inflammatory pain.- Interactions between kinins and the inflammatory pain process.- Sensory neuropeptides, neurogenic inflammation and inflammatory cells.- Inflammatory pain and the joint.- Nerve growth factor and sensory nerve function.- The relationship between hyperalgesia and hyperresponsiveness in the lung.- Neuropeptides and the respiratory tract: Relevance to asthma and rhinitis.- Neuropeptides and the gut: Tachykinins and calcitonin gene-related peptide in intestinal inflammation and pain.- Regulation of meningeal blood flow by neuropeptides: Relevance to migraine.- Sensory peptides: Effects in ageing and wound healing.- Calcitonin gene-related peptides and their receptors.- Tachykinin receptors and the potential of tachykinin antagonists as clinically effective analgesics and anti-inflammatory agents.