This book is a practical guide to the optimal clinical management of preterm delivery, using the best available evidence of the time.This book is a practical guide to the optimal clinical management of preterm delivery, using the best available evidence of the time. The chapters are based on common clinical scenarios and each provides a comprehensive literature review followed by evidence-based recommendations on appropriate management.This book is a practical guide to the optimal clinical management of preterm delivery, using the best available evidence of the time. The chapters are based on common clinical scenarios and each provides a comprehensive literature review followed by evidence-based recommendations on appropriate management.This volume summarizes advances in the optimal clinical management of preterm labour, using the best available evidence of the time. The contributors (mostly practising clinicians) are all actively involved in research into the mechanisms, aetiology, treatment and associated outcomes of preterm labour. The chapters are based on common clinical scenarios and each provides a comprehensive literature review followed by evidence-based recommendations on appropriate management. A summary of the pathophysiology of parturition is provided, and the obstetric scenarios cover management of threatened preterm labour, management of preterm premature ruptured membranes and management of preterm labour with specific complications (such as intrauterine growth restriction). Other chapters include the epidemiology, prediction and prevention of preterm labour. Anaesthetic and paediatric issues are explored in depth, and there are chapters on the legal and organizational issues surrounding preterm labour.1. Epidemiology of preterm delivery Peter Daniellian and Marion Hall; 2. Biology of labour Andrew Thomson and Jane Norman; 3. Transcriptional regulation of labour associated genes Philip Bennett, Tamsin Lindstrom and Jennifer Louden; 4. Fetal outcome fl$