This book evaluates affective disorders which are a group of major mood disorders and also examines latest therapy techniques. Affective disorders have always been an intriguing subject of interest for clinicians for nearly a century. Knowledge about a pressing requirement for an evidence-based personalized method of treatment is rapidly developing in the field of psychiatry. Experts from across the globe have contributed in this book in order to make it a useful source of reference for students, clinicians, researchers, etc. Particular topics like bipolar disorder, major depression, and schizoaffective disorder have been elucidated extensively as well as topics like treatment resistant depression, neurobiological mechanisms underlying the pathogenesis, translational research and challenging stigma of severe mental illness are also discussed. Specific stress has been laid on new enhancements in Cognitive-Behavioral Therapy and on attention to causal mechanisms of behavior alteration in Cognitive-Behavioral Analysis System of Psychotherapy.