Recent Advances in Retinoblastoma Treatment [Hardcover]

This book is a comprehensive resource on the current understanding of retinoblastoma. It addresses all the essential aspects of retinoblastoma and its management, including: its molecular biology and genetics, management by focal treatment, intraarterial and intravitreal chemotherapy, electroretinogram monitoring of treatment, pharmacokinetic studies, high-risk features, treatment of metastatic disease, and long-term follow-up. The book represents a collaborative project involving ophthalmic oncologists, geneticists, pediatric oncologists, interventional neuroradiologists, electrophysiologists, and basic scientists who are at the forefront of their field. It is written in an accessible manner, and a wealth of tables, figures, and exemplary images are included to enhance the understanding of concepts.

CONTENTS

1???????????????????? Molecular Biology of Retinoblastoma

Scott D. Walter and J. William Harbour

2???????????????????? Challenges of Genetic Susceptibility Testing for Retinoblastoma

Megan Harlan Fleischut

3???????????????????? Technique of Intra-Arterial Chemotherapy for Retinoblastoma

Y. Pierre Gobin

4????????????? Technique, Safety and Toxicity of Intravitreal Chemotherapy for Retinoblastoma

Jasmine H. Francis

5???????? Electroretinogram Monitoring of Retinoblastoma Treatment

Scott E. Brodie

6???????? Pharmacokinetics of Chemotherapy Delivered by Ophthalmic Artery Super-Selective Infusion

Paula Schaiquevich and Guillermo L. Chantada

7???????? Drug Discovery and Repurposing for Retinoblastoma

Bhavneet Bhinder, Jeni P. Mahida, Glorymar del Valle Ib??ez Sanchez, Kathryn Champ, Christophe Antczak, and Hakim Djaballah

8???????? Management of High Risk Retinoblastoma