The Role of Micro-organisms in Non-infectious Diseases [Paperback]

Based on a symposium covering latest research, this volume contains contributions by international experts. They investigate the role that viruses play in certain diseases, and include discussions of animal models and human trials. Some of the chapters cover specifically: streptococci and rheumatic heart disease, Epstein-Barr infection and cancer, and molecular mimicry and autoimmune disease.Based on a symposium covering latest research, this volume contains contributions by international experts. They investigate the role that viruses play in certain diseases, and include discussions of animal models and human trials. Some of the chapters cover specifically: streptococci and rheumatic heart disease, Epstein-Barr infection and cancer, and molecular mimicry and autoimmune disease.Introduction: HLA, Plagues and People.- Section I: Autoimmune and Immunopathological Diseases.- 1 Streptococci and Rheumatic Heart Disease.- Antigens of the Streptococcal Cell.- The Cell Membrane.- Muramyl Peptide Peptidoglycans.- Group A Carbohydrate.- Lipoteichoic Acids.- M Protein.- Hyaluronate Capsule.- Rheumatogenic Streptococci.- Rheumatogenic Characteristics.- The Resurgence of ARF in the United States.- Streptococcal Antigens Cross-reactive with Human Tissues.- Autoantibodies and ARF.- Other Antibodies of Special Interest.- Cell-Mediated Immune Responses.- Host Factors.- Summary and Conclusions.- 2 Viruses and Myocarditis.- The Role of Coxsackie Viruses in Heart Disease.- Coxsackie-Induced Myocarditis.- Myosin-Induced Myocarditis in Mice.- Implications for Human Myocarditis.- Summary.- 3 The Role of Environmental Factors in Modulating Insulin Dependent Diabetes.- Insights From Animal Models.- The BioBreeding Rat.- The Non-obese Diabetic Mouse.- Environmental Modulation of Penetrance of Diabetogenic Susceptibility Genes in NOD Mice.- Environmental Factors as Biological Response Modifiers.- Viruses.- Bacterial Products.- Diabetogenic Catalysts in Natural Ingredient Diets.- Isolation ofl#˜