Sepsis: An Interdisciplinary Challenge [Paperback]

Despite the progress that has been made in intensive care medicine, sepsis and septic shock are still accompanied by a high mortality rate. In recent years, new therapeutic approaches have been developed on the basis of a better understanding of this complex condition. This monograph contains contributions by well-known scientists and clinicians in the fields of hygienics, microbiology, infectious diseases, physiology, surgery and intensive care medicine. It provides an up-to-date overview of the etiology, pathophysiology, prevention, and therapy of sepsis and its complications.Despite the progress that has been made in intensive care medicine, sepsis and septic shock are still accompanied by a high mortality rate. In recent years, new therapeutic approaches have been developed on the basis of a better understanding of this complex condition. This monograph contains contributions by well-known scientists and clinicians in the fields of hygienics, microbiology, infectious diseases, physiology, surgery and intensive care medicine. It provides an up-to-date overview of the etiology, pathophysiology, prevention, and therapy of sepsis and its complications.Sepsis: Clinical Definition and Incidence.- Epidemiology, Clinical Course, and Prognosis of Sepsis in 691 Patients.- Predisposing Factors and Host Defense Response to Sepsis and Septic Shock.- Pathophysiology of Sepsis and Septic Shock.- New Methods in the Microbiological Diagnosis of Septicemia.- Early Clinical, Laboratory and Hemodynamic Indicators of Sepsis and Septic Shock.- Useful and Useless Measures for Prevention of Infections and Sepsis in Intensive Care Patients.- Pattern of Endocrine Secretions in Sepsis.- Therapeutic Possibilities in the Adult Respiratory Distress Syndrome Associated with Sepsis.- Corticosteroids and Nonsteroidal Anti-inflammatory Agents in the Sepsis Syndrome.- Circulatory Abnormalities in the Sepsis Syndrome.- Sepsis and Myocardial Function.- Oxygen Transport and Tissue Oxygenation in SeplĂL