Part I: Diagnosis, Classification, and PrognosisClassification of Acute Leukemias: Perspective 1Wolf-Dieter Ludwig, Torsten Haferlach, and Claudia SchochClassification of Acute Leukemias: Perspective 2Frederick G. BehmPart II: Chemotherapeutic StrategiesA. Infant LeukemiasBiology and Treatment of Infant Leukemias: Perspective 1Rob PietersBiology and Treatment of Acute Leukemias in Infants: Perspective 2Gregory H. ReamanB. Childhood Acute Lymphoblastic LeukemiaTreatment of Childhood Acute Lymphoblastic LeukemiaMartin Schrappe and Martin StanullaTreatment of Childhood Acute Lymphoblastic Leukemia: The Dana-Farber Cancer Institute ALL Consortium PerspectiveLewis B. Silverman and Stephen E. SallanC. Acute Lymphoblastic Leukemia in Adolescents and Young AdultsTreatment of Acute Lymphoblastic Leukemia in Adolescents and Young Adults: Lessons Learned and Future DirectionsSima Jeha and Hagop M. KantarjianTreatment of Adolescents and Young Adults with Acute Lymphoblastic Leukemia: Children's Cancer Group TrialsJames NachmanD. Acute Lymphoblastic Leukemia in AdultsTreatment of Adult Acute Lymphoblastic Leukemia: Perspective 1Spero R. Cataland and Richard A. LarsonTreatment of Adult Acute Lymphoblastic Leukemia: Perspective 2Dieter Hoelzer and Nicola G?kbugetE. Central Nervous System Therapy for Acute Lymphoblastic LeukemiaCentral Nervous System-Directed Therapy for Acute Lymphoblastic LeukemiaJudith M. ChessellsDiagnosis, Prophylaxis, and Treatment of Central Nervous System Involvement in Acute Lymphoblastic LeukemiaAnjo J. P. VeermanF. Relapsed Acute Lymphoblastic LeukemiaTreatment of Relapsed Acute Lymphoblastic Leukemia: Perspective 1Helmut Gadner, Georg Mann,and Christina PetersTreatment of Relapsed Acute Lymphoblastic Leukemia: Perspective 2G?nter Henze and Arend von StackelbergG. B-Cell Acute Lymphoblastic LeukemiaTreatment of B-Cell Acute Lymphoblastic Leukemia: Perspective 1Catherine PatteTreatment of B-Cell Acute Lymphoblastic Leukemia: Perspective 2John T. SandlundHlĂ